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Method of preimplantation genetic diagnostics in IVF programs

Official statistics from the World Health Organization confirm that the risk of having a child with chromosomal abnormalities increases with age. Moreover, this trend does not depend on the method of fertilization: the risk is present in both natural and artificial conception. The solution is the genetic analysis of the embryo with IVF. The procedure will not only improve the effectiveness of infertility treatment, but also protect the unborn child from chromosomal abnormalities.

Preimplantation genetic screening: what is included in the study?

Gene abnormalities in embryos are one of the main causes of failed IVF protocols. To get around this, fertility doctors recommend PGT. This early diagnosis allows the most efficient selection of healthy embryos for transfer to the uterus. Genetic predictive testing detects chromosomal abnormalities that can cause fetal defects such as:

  • Down syndrome;
  • Klinefelter’s disease;
  • Shereshevsky-Turner syndrome;
  • Patau disease and so on.

Diagnosis of possible defects is carried out before the woman becomes pregnant. And this is one of the main advantages of the method.

The analysis of the embryo for genetics is a complex of laboratory measures for the study of chromosomes. The procedure is accompanied by the IVF protocol. The embryo obtained as a result of artificial insemination is checked for chromosomal defects.

There are different formats for preimplantation genetic diagnosis. The price depends on the completeness of the survey. The analysis can be carried out:

  • 5 main chromosomes: 13, 18, 21, X, Y;
  • 24 chromosome pairs each: NGS and aCGH methods;
  • 24 chromosomes: NGS and aCGH.

To increase the chances of a successful IVF pregnancy , a complete examination of all 24 chromosomes is recommended.

Which specialist performs the genetic analysis?

The Lada Reproductive Health Clinic provides qualified chromosomal diagnostics services. To receive an appointment, you need consultation with a fertility specialist .

The procedure is performed by experienced embryologists. The clinic uses the most modern highly sensitive equipment for testing the human genome using the next generation sequencing method – NGS. This technology decodes genetic information by determining the primary structure of nucleotide sequences encoded in the embryo’s DNA.

An innovative diagnostic tool allows doctors to accurately identify various chromosomal abnormalities at the earliest stages of embryonic development. Thanks to this, the patients of the Lada clinic can protect their future children from serious genetic diseases.

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Клиника репродуктивного здоровья "Лада"
ул. Среднефонтанская, 19В, ЖК «Чудо-город» 65039 Украина, г.Одесса
(0482) 373747, [email protected]