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IntraCytoplasmic Sperm Injection or ICSI is the so-called auxiliary method, widely used by reproductive doctors around the world and in Odessa in particular.

As a rule, ICSI acts as an additional measure in the IVF procedure and helps a couple to conceive a child, even if the husband is diagnosed with complex forms of infertility, and the woman has problems with natural conception.

Indications for ICSI

When carrying out the IVF procedure and its successful completion, it is necessary that 1 ml of sperm contains about 20 million sperm, which have good mobility and do not carry genetic risks. However, in some cases, there may be a violation of the male reproductive function, to which you can add some features of the female body, which is a direct indication for the use of the IntraCytoplasmic Sperm Injection method.

In general, the indications for IVF with ICSI in Odessa include the following factors:

  • sperm has a low fertilizing ability, which can be expressed in a small amount of sperm in the seminal fluid, their mobility, a high content of pathological sperm, etc.);
  • ejaculate does not contain or contains minimally active and healthy sperm;
  • features of the structure of the egg, which can be caused by the age of a woman (as a rule, after 40 years, the membrane of the egg becomes denser, which prevents the sperm from penetrating inside, even with normal activity);
  • unsuccessful attempts at classical in vitro fertilization in a couple earlier.

Not so long ago, such diagnoses as retrograde ejaculation, azoospermia, severe oligozoospermia, ACAT were a direct indication for the use of donor sperm during IVF. However, today, thanks to IntraCytoplasmic Sperm Injection, as well as modern diagnostic capabilities in Odessa, all these diagnoses can be successfully circumvented, allowing the couple to conceive a blood child for both parents.

How is the procedure

In order for the female reproductive cell to accept the male genetic material and fertilization, it is necessary to select the fastest and most mobile sperm, which is then artificially injected into the cavity of the egg under laboratory conditions.

When carrying out all the necessary manipulations, special equipment is used, which makes it possible to perform the necessary actions with a certain accuracy and effort, which will not damage the biomaterial.

For a successful procedure, a microscope is used, where with the help of a manipulator that converts the movements of the specialist’s hands into micromotions, the previously selected sperm is injected with a thin microneedle made of glass, directly into the cavity of the egg. After a successful fertilization process, under special laboratory conditions, the embryo reaches the blastocyst stage and then is implanted into the uterine cavity of the expectant mother, where it continues its natural development.

Years of research and widespread use of IVF with ICSI in Odessa have led to the fact that today its success is approximately 85% of successful fertilizations and further pregnancy. It should be said for comparison that in a healthy couple planning a pregnancy, conception is naturally possible with a 20% probability in one menstrual cycle.

Of course, in our time there are a number of problems that are in one way or another related to the reproductive health of men and women, however, thanks to modern diagnostic and treatment options, many of them are surmountable, which gives everyone a chance to become a mom and dad.


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Клиника репродуктивного здоровья "Лада"
ул. Среднефонтанская, 19В, ЖК «Чудо-город» 65039 Украина, г.Одесса
(0482) 373747, [email protected]