The method is applied when the spouses are planning to have a second child or if the prior attempt failed. It is a reliable and proven technique. There were no negative effects on the course of pregnancy and fetus detected, that could be related to the cryopreservation and storage at low (-196ºС) temperature.
Cost of storage, embryo thawing and transfer is by an order lower that the so-called “fresh” IVF attempt, which is why the embryo cryopreservation is more economically beneficial.
Married couples who apply to the extracorporeal fertilization centers are often asking doctors about the success level of embryo cryopreservation programs available in such centers.
The extracorporeal fertilization program often comes with a greater number of embryos than it is required for one transfer. If required, they may be stored for future IVF attempts. In addition, same married couple may decide to have another baby in the future, therefore, this method exists to avoid putting additional load on the mother’s organism.
What is embryo cryopreservation?
Cryopreservation is a safe method of freezing and storage of embryos in the nitrogen vapors at a temperature of -196ºС. Application of such low temperature allows stopping all biochemical processes in the cells and storing them for a long time.
Advantages of embryo cryopreservation
The cryopreservation program has a number of significant advantages:
- Reduction of repeated ovarian stimulations and follicular punctures, which considerably reduces the load of medications on the female organism
- Great savings of patient’s funds for purchase of additional medications
- Prevention of ovarian hyperstimulation syndrome
- Possibility to conceive a child in a few years, including after the treatment of oncological diseases
- Possibility of donating the embryos to other infertile families
Frozen embryos can be stored for as much as it is needed — from several months to several decades. Each couple shall individually decide the fate of their embryos: to stop their storage, to continue storing them, transfer to the uterus, to provide them for scientific researches, transport them to a different clinic or donate them to an infertile couple.
Does the cryopreservation of embryos influence the IVF outcome and development of children?
The process of frozen embryos storage does not have influence on their further development; however, they can be damaged during freezing and thawing. That said, their survival rate after vitrification is much higher (more than 98%) than after the slow freezing (it can be around 50%). Due to this reason, we use the vitrification process at our Clinic.
Children born from a pregnancy with use of thawed embryos do not differ from other children in any way: it is proven by a huge number of babies born from “cryo-pregnancies”.